Bacitacin is a product of bacillus subtillis and chemicllyis a polypeptide.Bacause of its toxicity to animal and human cells its not used for systemic chemotherapy. It does have application for topical treatement of infections caused by Gram-positive bacteria.
Bacitracin interferes with regeneration of the monophosphate form of bectoprenol from the pyrophosphate form.
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